Infrastructure

Next Generation Sequencing (NGS)

Illumina’s Miseq desktop sequencer allows sequencing of targeted panels and is ideally suited for development of sequencing based diagnostic assays, for the clinic. A MiSeq can sequence one to 96 samples in parallel, depending upon the target size for sequencing. The MiSeqDx instrument is the first and only FDA-cleared in vitro diagnostic (IVD) next-generation sequencing (NGS) instrument. Designed specifically for the clinical laboratory environment, the MiSeqDx has an approximately 4 square feet footprint, an easy-to-follow workflow, and data output tailored to the needs of clinical labs. A standard sequencer can output 7-12 GB of raw sequence data.
It supports sequencing of target libraries prepared using a wide range of technologies; both PCR amplicon based as well as probe hybridization based enrichment. The MiSeqDx instrument provides an easy-to-use, automated workflow. The compact, all-in-one instrument incorporates cluster generation, paired-end fluidics, sequencing by synthesis chemistry, and complete data analysis. An intuitive touch screen interface makes for simple instrument operation.